Epigenetic Mechanisms Regulating The Transcription of BBB Genes: Role of Wnt/β-catenin signaling

ABSTRACT: To identify CNS endothelial cell (EC) the gene cohorts that participate in blood brain barrier (BBB) formation versus maintenance. We investigated mechanism behind the reduced Wnt/β-catenin signaling observed in adult CNS ECs We also investigated whether the adult endothelial cells can re express the EC gene cohorts required for the BBB formation.

ORGANISM(S): Mus musculus

PROVIDER: GSE255967 | GEO | 2024/08/02

REPOSITORIES: GEO