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Homeodomain-like domain of Plasmodium berghei HDP1 binds to TGCACA motif.

ABSTRACT: To investigate the DNA-binding property of homeodomain-like domain of Plasmodium berghei HDP1, DNA immunoprecipitation followed by high-throughput sequencing (DIP-seq) analysis were performed. Recombinant homeodomain-like domain fused with glutathione S-transferase were mixed with the P. berghei genomic DNA fragmented via sonication, and protein-DNA complex was harvested using glutathione-sepharose resin. The obtained DNA fragments were sequenced via the next generation sequencing.

ORGANISM(S): Plasmodium berghei ANKA

PROVIDER: GSE256093 | GEO | 2024/02/25

REPOSITORIES: GEO

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