Effect of GSK3 inhibition on the transcriptional signature of human monocytes

ABSTRACT: We explored the molecular impact of blocking GSK3 on the gene expression profile in human monocytes. GSK3 inhibition by CHIR-99021 redirected monocytes towards acquiring an anti-inflammatory gene profile similar to M-CSF-primed monocyte-derived macrophages.

ORGANISM(S): Homo sapiens

PROVIDER: GSE256538 | GEO | 2025/04/16

REPOSITORIES: GEO