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Escape from X inactivation is directly modulated by Xist non-coding RNA [ATAC-seq]

ABSTRACT: X-chromosome inactivation silences one copy of the X-chromosome in female cells, but a number of genes escapes this inactivation. We asked whether increased levels of Xist RNA, the molecular actor driving X-inactivation, impacts epigenetic marks around escapees. To this end, we performed chromatin accessibility profiling of X-linked genes in clonal neural progenitor cell lines to identify cis-regulatory elements active in these cell lines.

ORGANISM(S): Mus musculus

PROVIDER: GSE259398 | GEO | 2025/12/09

REPOSITORIES: GEO

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