Genomics

Dataset Information

16

Inducible Astrocytomas in Genetically Engineered Mice


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

INSTRUMENT(S): [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

SUBMITTER: Burak Kutlu   

PROVIDER: GSE26069 | GEO | 2012-09-13

SECONDARY ACCESSION(S): GSE26068GSE26002PRJNA135109

REPOSITORIES: GEO

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Publications


Glioblastoma (GBM), the most common brain malignancy, remains fatal with no effective treatment. Analyses of common aberrations in GBM suggest major regulatory pathways associated with disease etiology. However, 90% of GBMs are diagnosed at an advanced stage (primary GBMs), providing no access to early disease stages for assessing disease progression events. As such, both understanding of disease mechanisms and the development of biomarkers and therapeutics for effective disease management are l  ...[more]

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