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Role of SMN Protein in regulating the transcription and alternative splicing of Pulmonary Vascular Remodeling-Related Genes in HPASMCs

ABSTRACT: To explore the effect of SMN protein on alternative splicing of multiple genes in human pulmonary artery smooth muscle cells (HPASMCs), we used shRNA specifically against the SMN to knock down the expression of SMN protein.Human primary pulmonary artery smooth muscle cells (hPASMCs) of donors were obtained from China Center for Type Culture Collection (Wuhan, Hubei, China).

ORGANISM(S): Homo sapiens

PROVIDER: GSE261233 | GEO | 2024/03/15

REPOSITORIES: GEO

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RNAseq of Extracellular vesicle RNAs and cellular RNAs from HPASMCs with or without TGF-b1 or BMP4 treatment

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