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Stress-regulated miR-708-5p affects recognition memory and manic-like behavior through Neuronatin downregulation.

ABSTRACT: microRNAs are posttranscriptional regulators that bind to target mRNAs. We tested the regulatory effect of miR-708-5p, a miRNA associated with Bipolar Disorder, in the mouse hippocampus. To unveil molecular mechanisms downstream of miR-708-5p, we stereotactically injected a virus overexpressing miR-708-5p for target discovery.

ORGANISM(S): Mus musculus

PROVIDER: GSE261288 | GEO | 2024/03/18

REPOSITORIES: GEO

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