A humanized therapeutic monoclonal anti-ASC antibody alleviates oxygen-induced retinopathy in mice

ABSTRACT: This study was to test the efficacy of a humanized monoclonal antibody, IC100 for ASC, an apoptosis-associated speck-like protein containing a caspase recruitment domain that is pivotal in inflammasome assembly, in the prevention and treatment of an oxygen-induced retinopathy (OIR) mouse model.

ORGANISM(S): Mus musculus

PROVIDER: GSE261490 | GEO | 2025/05/01

REPOSITORIES: GEO