Ifi27l2a regulates the microglial inflammation in the context of aging and stroke

ABSTRACT: Microglia are key mediators of inflammatory responses within the brain, as they regulate pro-inflammatory responses while also limiting neuroinflammation via reparative phagocytosis. To facilitate identification of potential mediators of inflammation, we performed single-cell RNA sequencing of aged mouse brains following stroke and found that Ifi27l2a was significantly up-regulated, particularly in microglia.

ORGANISM(S): Mus musculus

PROVIDER: GSE261494 | GEO | 2025/01/09

REPOSITORIES: GEO