Gene expression of lymphoma tissues from FBW7 KO mice

ABSTRACT: During maturation of hematopoietic stem/progenitor cells (HSPCs) to fully differentiated mature B lymphocytes, developing lymphocytes may undergo malignant transformation and produce B-cell lymphomas. Emerging evidence shows that through the endothelial-hematopoietic transition, specialized endothelial cells called the hemogenic endothelium can differentiate into HSPCs. However, the contribution of genetic defects in hemogenic endothelial cells to B-cell lymphomagenesis has not yet been investigated. /

ORGANISM(S): Mus musculus

PROVIDER: GSE261525 | GEO | 2024/03/18

REPOSITORIES: GEO