Impact of CDK7 inhibition across a range of inhibitors in the context of heat shock

ABSTRACT: Here we evaluate the effect of CDK7 inhibition in the context of heat shock across three distinct inhibitors. Two inhibitors are Syros compounds SY-5609 and SY-5102. The final inhibitor is 3MBPP1 in a CDK7 analog sensitive cell line. We find that overall the same gene programs are impacted.

ORGANISM(S): Homo sapiens

PROVIDER: GSE261649 | GEO | 2025/02/14

REPOSITORIES: GEO