Association of hepatitis B virus genomes with active chromatin hubs challenges host replication fidelity, leading to DNA damage.

ABSTRACT: We have developed a modified iteration of a viral chromosome conformation capture (V3C-seq) assay to degrade non-cccDNA to show that the HBV cccDNA localizes spatially with cellular sites of DNA damage.

ORGANISM(S): Homo sapiens

PROVIDER: GSE261927 | GEO | 2024/03/24

REPOSITORIES: GEO