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Effect of Lactate dehydrogenase inhibitor (LDHi; GSK2837808A) on BCG vaccine induced trained immunity in vitro

ABSTRACT: Trained immunity is the phenomenon whereby innate immune cells such as monocytes or macrophages undergo functional reprogramming after exposure to certain microbial components, altering their responses to future exposures. This study examined the in vitro effect of an LDH inhibitor on BCG induced trained immunity in human primary monocytes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE262099 | GEO | 2025/04/30

REPOSITORIES: GEO

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| PRJNA1090316 | ENA