Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Geneship analysis of porcine femoral arteries after minimally invasive repair by different means of closure

ABSTRACT: After observing the surgical wounds on the 28th postoperative day, the experimental animals were put to death. Vascular tissues from the surgical site were taken and subjected to gene microarray analysis. This was used to examine the effect of TAG repair in the experimental group and Exoseal repair in the control group.

ORGANISM(S): Sus scrofa

PROVIDER: GSE262367 | GEO | 2024/03/30

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Caveolar disruption causes contraction of rat femoral arteries via reduced basal NO release and subsequent closure of BKCa channels.

Project description: Not available

| S-EPMC4451037 | biostudies-literature

Transcription profiling of rat gastrocneumius muscle following short and long term denervation

Project description:Effect of "Sensory Protection" on the transcriptome of Gastrocnemius muscle denervated by Tibial nerve transection in the rat. Comparison is made between the muscle transcriptome in denervated muscle (D), muscle undergoing surgical repair with a motor nerve (immediate repair, or IR) and muscle undergoing surgical repair with a pure sensory nerve (sensory protection, or SP). There are 6 cohorts of rats with 4 to 6 rats in each cohort:<br><br>1 Month Denervated, 1 Month Immediate Repair, 1 Month Sensory Protection, 3 Month Denervated, 3 Month Immediate Repair, 3 Month Sensory Protection. <br><br>For each animal RNA was extracted from both the experimental operated (right) gastrocnemius muscle and the contralateral control unoperated (left) gastrocnemius. Samples were run in duplicate with fluorophor reversal experiments (i.e experimental limb RNA labelled with Cy3 and control limb RNA labelled with Cy5 and vice versa) to control for possible unequal incorporation of the dyes in the reverse transcription reaction.

2009-04-15 | E-MEXP-1580 | biostudies-arrayexpress

Rat hindlimb arteries: Shunt versus Control

Project description:Arteriogenesis is defined as the development of a collateral circulation, bypassing an arterial occlusion. We have previously demonstrated that chronically elevated fluid shear stress completely normalized blood flow in femoral artery ligated rabbits. This was realized by a surgical intervention: the creation of an arterio- venous anastomosis (shunt) between the femoral artery and the accompanying vein. The aim of this study was a gene profiling approach in order to identify differentially expressed genes during collateral growth in the shunt model when compared to pre-existent collaterals (sham).

2010-05-26 | GSE16359 | GEO

Primary angle closure glaucoma is characterized by altered extracellular matrix homeostasis in the iris

Project description:Purpose. To characterize the proteome of the iris in primary angle closure glaucoma (PACG). Experimental Design. In this cross-sectional study, iris samples were obtained from surgical iridectomy of 48 adults with PACG and five normal controls. Peptides from iris were analyzed using liquid chromatography-tandem mass spectrometry on an Orbitrap Q Exactive Plus mass spectrometer. Verification of proteins of interest was conducted using selected reaction monitoring on a triple quadrupole mass spectrometer. The main outcome was proteins with a log2 two-fold difference in expression in iris between PACG and controls. Results. There were 3,446 non-redundant proteins identified in human iris, of which 165 proteins were upregulated and 251 proteins were downregulated in PACG compared with controls. Thirty-two upregulated proteins were either components of the extracellular matrix (ECM) (fibrillar collagens, EMILIN-2, fibrinogen, fibronectin, matrilin-2), matricellular proteins (thrombospondin-1), proteins involved in cell-matrix interactions (integrins, laminin, histidine-rich glycoprotein, paxillin), or protease inhibitors known to modulate ECM turnover (-2 macroglobulin, tissue factor pathway inhibitor 2, papilin). Two giant proteins, titin and obscurin, were up- and down-regulated, respectively, in the iris in PACG compared with controls. Conclusions and Clinical Relevance. This proteomic study shows that ECM composition and homeostasis is altered in the iris in PACG.

2022-03-01 | PXD022292 | Pride

Midterm Results Following Minimally Invasive Distal Chevron Osteotomy: Comparison With the Minimally Invasive Reverdin-Isham Osteotomy by Means of Meta-analysis.

Project description: Not available

| S-EPMC8286526 | biostudies-literature

Antegrade common femoral artery closure device use is associated with decreased complications.

Project description: Not available

| S-EPMC7718979 | biostudies-literature

3D modelling of drug-coated balloons for the treatment of calcified superficial femoral arteries.

Project description: Not available

| S-EPMC8504744 | biostudies-literature

A Minimally Invasive Experimental Model of Acute Ocular Hypertension with Acute Angle Closure Characteristics.

Project description: Not available

| S-EPMC7414621 | biostudies-literature

Femoral veins and pulmonary arteries stranded paired-end reads with induced VTE, retrieved from RNA-seq.

Project description:A new experimental porcine model of venous thromboembolism and transcriptomic analysis of deep vein thrombosis in the femoral veins.

| PRJEB43020 | ENA

Differences of bleedings after percutaneous coronary intervention using femoral closure and radial compression devices.

Project description: Not available

| S-EPMC6531194 | biostudies-literature