Chemically induced expansion of type 2 alveolar epithelial cell promotes regenerative lower airway repair

ABSTRACT: To evaluate the effect of DPP4 inhibitor on regenerative repair of the lung upon injury, we carried out a single cell RNA sequencing study. In this study, orally administered sitagliptin was tested in LPS-induced lung injury model, followed by longitudinal single cell transcriptomic analysis with lung cells harvested at indicated time points.

ORGANISM(S): Mus musculus

PROVIDER: GSE262393 | GEO | 2024/03/27

REPOSITORIES: GEO