ATV-TfR and ATV-CD98hc biodistribution in the mouse brain

ABSTRACT: We evaluated the distributions of transferrin receptor (TfR)- and CD98 heavy chain (CD98hc)-targeting antibody transport vehicles (ATVs) in mouse brain using systemically injected fluorescently tagged ATVs. Combining FACS sorting with scRNA-seq, we report the localization of ATV-TfR and ATV-CD98hc on brain endothelial cells and their unique distribution across parenchymal brain cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE262436 | GEO | 2024/10/02

REPOSITORIES: GEO