Gene expression profile of FACS sorted cranial neural crest cells from E12.5-E13.5 mouse embryonic head

ABSTRACT: Craniofacial morphogenesis depends on complex cell fate decisions during the differentiation of post-migratory cranial neural crest cells. Molecular mechanisms of cell differentiation of mesenchymal cells to developing bones, cartilage, teeth, tongue, and other craniofacial tissues are still poorly understood. We performed single-cell transcriptomic analysis of craniofacial mesenchymal cells derived from cranial NCCs in mouse embryo. Using FACS sorting of Wnt1-Cre2 progeny, we carefully map the cell heterogeneity in the craniofacial region during the initial stages of bone and cartilage formation.

ORGANISM(S): Mus musculus

PROVIDER: GSE262468 | GEO | 2024/10/29

REPOSITORIES: GEO