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Transcriptional characterization of mouse and rat ventral pallidum using single nucleus RNA-sequencing

ABSTRACT: The ventral pallidum (VP) was defined as a basal ganglia nucleus and a major output of the nucleus accumbens. It is known to be involved in motivated behaviors, including feeding. We sought to further characterize VP by sequencing the RNA from individual nuclei in mouse and rat VP and analyzing neuronal expression patterns. We also investigated the impact of a high-fat diet on VP transcription. These data will be useful for understanding cell type diversity in VP, homology between mouse and rat VP, and the impact of diet on VP gene expression.

ORGANISM(S): Mus musculus Rattus norvegicus

PROVIDER: GSE262729 | GEO | 2025/10/07

REPOSITORIES: GEO

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