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Dysferlin deficiency modulates the proximal-distal muscle transcriptome

ABSTRACT: By comparing the transcriptome from proximal (quadriceps femoris, QF) and distal (tibialis anterior, TA)muscle groups in dysferlin deficient mouse muscle (the SJL mutation bred onto C57BL/10 to produces C57BL/10-SJL.Dysf) with proximal and distal muscle groups from control C57BL/10 mice of an equivalent age (3-weeks old, prior to the onset of overt pathology) we aim to address the issues of muscle selectivity in this this form of muscular dystrophy. Keywords: parallel sample

ORGANISM(S): Mus musculus

PROVIDER: GSE2629 | GEO | 2005/05/06

SECONDARY ACCESSION(S): PRJNA92145

REPOSITORIES: GEO

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Transcription profiling of proximal and distal muscle groups in dysferlin-deficient mice (C57BL/10.SJL_Dysf) to understand selective pattern of muscle involvement in muscular dystrophies

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Project description:Dysferlin deficiency modulates the proximal-distal muscle transcriptome

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