Variants in tubule epithelial regulatory elements mediate most heritable differences in human kidney function

ABSTRACT: We used bulk and single-cell ATAC-seq to measure chromatin accessibilty in human kidneys. This allowed us to define candidate cis-regulatory elements of each human kidney cell type and identify the role of podocyte and tubule regulatory elements in human kidney function.

ORGANISM(S): Homo sapiens

PROVIDER: GSE262931 | GEO | 2024/07/05

REPOSITORIES: GEO