Analysis of retroviral MLT1 enhancer-driven genes identifies over-expression of EPS8L1 as an early-stage initiator of both oxidative stress and poor trophoblast invasiveness in the pregnancy disorder preeclampsia
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ABSTRACT: In the human-specific disorder of pregnancy preeclampsia (PE) we find dysregulation of multiple genes associated with the cis-regulatory elements (CREs) derived from mammalian-specific endogenous retrovirus (ERV3-MLT1)
ORGANISM(S): Homo sapiens
PROVIDER: GSE263305 | GEO | 2024/04/08
REPOSITORIES: GEO
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