S100A8/A9 activate key genes and pathways in colon tumor progression

ABSTRACT: Studies using bone marrow chimeric mice revealed that S100A8/A9 expression on myeloid cells is essential for development of colon tumors. Our results thus reveal a novel role for myeloid-derived S100A8/A9 in activating specific downstream genes associated with tumorigenesis and in promoting tumor growth and metastasis.

ORGANISM(S): Mus musculus

PROVIDER: GSE26359 | GEO | 2011/02/01

SECONDARY ACCESSION(S): PRJNA135039

REPOSITORIES: GEO