Project description:CD73ko and control mice were subjected to transient middle cerebral artery occlusion (tMCAO) for 50min or subjected to equally long sham surgery. Whole brain RNA was isolated and analyzed with the NanoString nCounter® mouse glial profiling panel.
Project description:Transcriptional profiling of host immune response in brains of mouse model of cryptococcal post-infectious inflammatory response syndrome (cPIIRS), cPIIRS mice treated with Ruxolitinib, and naïve control mice using the NanoString nCounter Mouse Neuroinflammation Panel v1.0. NanoString nCounter assay was performed to measure the expression of neuroinflammatory genes in the brains of cPIIRS mice (C57BL/6Tac, 21 day post-infection) compared to cPIIRS mice treated with Ruxolitinib, and naïve mice.
