Genomics

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Gene expression profile of SYT-SSX2-expressing human bone marrow-derived mesenchymal stem cells


ABSTRACT: Synovial sarcoma is a rare malignancy characterized by the presence of a specific chromosomal translocation t(X;18) that results in the formation of a fusion protein SYT-SSX. Because it is believed that synovial sarcoma arises from mesenchymal stem or progenitor cells, we used human bone marrow-derived mesenchymal stem cells (MSCs) to determine the changes in gene expression caused by this oncogene in untransformed MSCs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE26563 | GEO | 2011/09/26

SECONDARY ACCESSION(S): PRJNA142227

REPOSITORIES: GEO

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