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Single-cell multi-omic dataset mapping chromatin modifications and transcriptome during zebrafish development

ABSTRACT: Establishing a cell-type-specific chromatin landscape is crucial for the maintenance of cell identity during embryonic development. However, our knowledge of how this landscape is set during vertebrate embryogenesis has been limited, due to the lack of methods to jointly detect chromatin modifications and gene expression in the same cell. In this study, we apply T-ChIC, a method for joint profiling of histone modifications and transcriptome of single cells, to study the early embryonic development in Zebrafish (4-24 hpf).

ORGANISM(S): Danio rerio

PROVIDER: GSE265874 | GEO | 2025/08/18

REPOSITORIES: GEO

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