Modification of fat mass through targeting distal enhancer of Ptrf

ABSTRACT: We revealed a close positive relationship between Ptrf transcription and adipose mass in mice, and single-nucleus transcriptomics indicated the involment of impariment of adipogenic differentiation, adipocyte metabolism, transportation of multiple nutrients and altered regulatory network in Ptrf knockout-induced decrease of fat mass.

ORGANISM(S): Mus musculus

PROVIDER: GSE266197 | GEO | 2025/08/08

REPOSITORIES: GEO