Transcriptomics

Dataset Information

20

Development of microRNA expression signatures for gastric cancer


ABSTRACT: To further investigate of microRNA expression profile of gastric cancer, we have employed whole microRNA gene chip as a discovery platform to identify gene differential expression between gastric cancer tissues with mormal gastric tissues.Expression of four microRNAs (miR-125b,miR-451,miR-192b,miR-200b) from this signature was quantified and verified in the same RNA samples by real-time PCR. Overall design: A total of 4 consecutive patients with gastric cancer undergoing elective surgery were entered into this study. After obtaining informed consent from the patients and after receiving the approval of the ethics committee, the following tissue samples were collected: tumor (3 × 3 × 5 mm) and adjacent normal tissues (3 × 3 × 5 mm).

INSTRUMENT(S): Agilent-021827 Human miRNA Microarray [miRNA_107_Sep09_2_105]

ORGANISM(S): Homo sapiens  

SUBMITTER: Hong Xia Wang   

PROVIDER: GSE26645 | GEO | 2011-01-15

SECONDARY ACCESSION(S): PRJNA136375

REPOSITORIES: GEO

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