AMH protects the ovary from doxorubicin by regulating cell fate and the response to DNA damage

ABSTRACT: we aim to explore the single-cell mechanisms behind ovarian damage in prepubertal mice following doxorubicin (DOX) treatment, and how Anti-Müllerian hormone (AMH) prevents chemotherapy-induced pathological damage, using single-cell RNA sequencing as well as quantitative and morphometric histological evaluation.

ORGANISM(S): Mus musculus

PROVIDER: GSE266600 | GEO | 2024/05/24

REPOSITORIES: GEO