Epigenetic scars in regulatory T cells are retained after successful treatment of chronic hepatitis C with direct-acting antivirals [RNA-Seq]

ABSTRACT: During chronic HCV infection, several immune components are altered both quantitatively and qualitatively. The recent introduction of DAAs led to a high cure rate of chronic HCV infection. Nevertheless, we have demonstrated that inflammatory features of TREG cells are maintained at phenotypic, transcriptomic, and epigenetic levels even after successful DAA treatment.

ORGANISM(S): Homo sapiens

PROVIDER: GSE266895 | GEO | 2025/09/19

REPOSITORIES: GEO