Impact of parental obesity on adipose progenitor programming

ABSTRACT: Parental obesity (PO) increases the risk of obesity and metabolic syndromes in offspring. To investigate how PO influences adipose progenitors, we generated offspring from lean (Ln-F1) or obese (Ob-F1) parents and isolated the stromal vascular fraction (SVF) from inguinal white adipose tissue (iWAT) depots at postnatal day 21 (P21). Bulk RNA sequencing of the SVF was performed to uncover the molecular mechanisms by which PO programs adipose progenitors.

ORGANISM(S): Mus musculus

PROVIDER: GSE267285 | GEO | 2025/07/22

REPOSITORIES: GEO