Gene expression profile at single cell level of CD45+ cells that were isolated from the lung of anti-PD-1 Ab-treated young or aged mice

ABSTRACT: In tumor-bearing aged mice, abberant immune cells are expected to be accumulated in damaged lung of aged mice in response to anti-PD-1 therapy. To identify subpopulation responsible for the lung damage, we analyzed for differences in CD45+ immune cell components isolated from the lung of young and aged mice, using single-cell RNA sequencing (scRNA-seq).

ORGANISM(S): Mus musculus

PROVIDER: GSE267557 | GEO | 2024/12/31

REPOSITORIES: GEO