Mutant IDH modulates suppressive myeloid populations in malignant glioma

ABSTRACT: RNA-sequencing for myeloid inflammation-related genes was conducted on primary tumor samples from patients with IDH-wildtype glioblastoma (GBM) and grade 4 IDH-mutant astrocytoma (G4IMA). In addition, the IDH-wildtype murine glioma cell line GL261 and a strain of IDH-mutant GL261 were also sequenced using the murine counterpart of the RNA-sequencing myeloid innate immunity panel.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE268118 | GEO | 2024/05/29

REPOSITORIES: GEO