Methylation profiling

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Genome-wide DNA methylation analysis of driver genes in blood of high-altitude pulmonary edema


ABSTRACT: High Altitude Pulmonary Edema (HAPE) is a disease that interacts with environmental and epigenetic factors with a severe clinical course and high mortality rate. This study aims to investigate DNA methylation alterations of HAPE and identify the driver genes. The Illumina Infinium MethylationEPIC BeadChip (850K) was used to obtain DNA methylation profiles across 860,000 CpGs in blood of 6 HApe patients and 6 healthy volunteers.

ORGANISM(S): Homo sapiens

PROVIDER: GSE268584 | GEO | 2025/07/30

REPOSITORIES: GEO

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