Spatially clustered type I interferon responses at injury borderzones [scRNA-Seq]

ABSTRACT: Sterile inflammation post-myocardial infarction was thought to be driven by myeloid cells, however, we show that borderzone cardiomyocytes are the critical initators of the Type I Interferon response through spatial, single-cell, and single-nuclei transcriptomics.

ORGANISM(S): Mus musculus

PROVIDER: GSE268876 | GEO | 2024/08/06

REPOSITORIES: GEO