NAT10 is identified as a novel driver for brain metastasis

ABSTRACT: Metastatic breast cancer remains a major cause of cancer related deaths in women and there are few effective therapies against this advanced disease. Using in vivo and in vitro genetic screens, we identified NAT10 as a driver for breast cancer brain metastassis. Here, we profile the transcriptome of metastatic breast cancer cells MDA-MB-231-BrM3 following NAT10 knockdown, aiming to identify the downstream effectors of NAT10.

ORGANISM(S): Homo sapiens

PROVIDER: GSE269160 | GEO | 2024/11/24

REPOSITORIES: GEO