Transcriptomics

Dataset Information

0

RNA-seq revealed the protective effect of Huangqi Guizhi Wuwu Decoction against cisplatin induced PC12 cell injury


ABSTRACT: Chemotherapy-induced peripheral neuropathy (CIPN) not only impacts chemotherapy regimens but also causes intolerable and long-lasting effects on cancer patients. Currently, duloxetine is the only drug used to treat CIPN. However, the clinical use of this drug still faces several challenges. Therefore, we focused on traditional Chinese medicine (TCM) to find an effective and safe alternative medicine. Huangqi Guizhi Wuwu Decoction (HGWD) is a traditional Chinese medicine that has been clinically used for treating nerve pain for thousands of years. This study aimed to investigate the neuroprotective effect of HGWD on cisplatin-induced injury in PC12 cells and to elucidate its potential mechanism of action.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE269389 | GEO | 2025/06/07

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2014-10-22 | E-GEOD-55268 | biostudies-arrayexpress
2023-06-30 | GSE212771 | GEO
2025-03-01 | GSE169076 | GEO
2014-10-22 | GSE55268 | GEO
2019-02-16 | PXD006342 | Pride
2018-04-26 | GSE109697 | GEO
2022-10-15 | PXD033627 | Pride
2014-10-16 | E-GEOD-62397 | biostudies-arrayexpress
2025-03-25 | GSE197043 | GEO
2018-06-13 | GSE115662 | GEO