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Effects of dexamethasone stimulation on gene expression in human trabecular meshwork cells

ABSTRACT: The changes in the trabecular meshwork in steroid-induced glaucoma are similar to those in human primary open-angle glaucoma. To explore the changes in the trabecular meshwork in POAG, we extracted RNA from human trabecular meshwork cells with or without dexamethasone, followed by next-generation transcriptome sequencing to observe changes in gene expression in trabecular meshwork cells, thereby better understanding the mechanism of increased IOP.

ORGANISM(S): Homo sapiens

PROVIDER: GSE269489 | GEO | 2025/10/28

REPOSITORIES: GEO

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