Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Deep Small RNA Sequencing from the Nematode Ascaris Reveals Conservation, Functional Diversification, and Novel Developmental Profiles

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

OTHER RELATED OMICS DATASETS IN: PRJNA136965PRJNA142039PRJNA63155PRJNA62057PRJNA142041

ORGANISM(S): Ascaris suum

PROVIDER: GSE26957 | GEO | 2011/06/16

SECONDARY ACCESSION(S): PRJNA136965

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles.

Project description: Not available

| S-EPMC3166831 | biostudies-literature

Deep Small RNA Sequencing from the Nematode Ascaris Reveals Conservation, Functional Diversification, and Novel Developmental Profiles

Project description:Deep Small RNA Sequencing from the Nematode Ascaris Reveals Conservation, Functional Diversification, and Novel Developmental Profiles

| PRJNA136965 | ENA

Small RNA pathways in the nematode Ascaris in the absence of piRNAs.

Project description: Not available

| S-EPMC8837657 | biostudies-literature

Cecropin P1 and novel nematode cecropins: a bacteria-inducible antimicrobial peptide family in the nematode Ascaris suum.

Project description: Not available

| S-EPMC1184576 | biostudies-literature

Small RNA pathways in the nematode Ascaris in the absence of piRNAs

Project description:Small RNA pathways play diverse regulatory roles in the nematode C. elegans. However, our understanding of small RNA pathways, their conservation, and their roles in other nematodes is limited. Here, we analyzed small RNA pathways in the parasitic nematode Ascaris. Ascaris has ten Argonautes with five worm-specific Argonautes (WAGOs) that are associated with secondary 5’-triphosphate small RNAs (22-24G-RNAs). These Ascaris WAGOs and their small RNAs target repetitive sequences (WAGO-1, WAGO-2, WAGO-3, and NRDE-3) or mature mRNAs (CSR-1, NRDE-3, and WAGO-3) and are similar to the C. elegans mutator, nuclear, and CSR-1 small RNA pathways. Ascaris CSR-1 likely functions to “license” gene expression in the absence of an Ascaris piRNA pathway. Ascaris ALG-4 and its associated 26G-RNAs target and appear to repress specific mRNAs during meiosis in the testes. Notably, Ascaris WAGOs (WAGO-3 and NRDE-3) small RNAs change their targets between repetitive sequences and mRNAs during spermatogenesis or in early embryos illustrating target plasticity of these WAGOs. We provide a unique and comprehensive view of mRNA and small RNA expression throughout nematode spermatogenesis that illustrates the dynamics and flexibility of small RNA pathways. Overall, our study provides key insights into the conservation and divergence of nematode small RNA pathways.

2021-12-15 | GSE189061 | GEO

Conservation and diversification of small RNA pathways within flatworms.

Project description: Not available

| S-EPMC5594548 | biostudies-literature

Ascaris lumbricoides strain:Nematode

Project description:Ascaris lumbricoides strain:Nematode Phenotype or Genotype

| PRJNA556423 | ENA

Genomics of the Parasitic Nematode Ascaris and Its Relatives.

Project description: Not available

| S-EPMC8065839 | biostudies-literature

Aberrant Ascaris suum Nematode Infection in Cattle, Missouri, USA.

Project description: Not available