CD137 expression in Foxp3+ regulatory T cells is important for controling the progression of type 1 diabetes

ABSTRACT: CD137-deficient Foxp3+ regulatory T cells display functional alterations compared to the wildtype counterpart. In this study, we used single-cell RNA sequencing to define the differentiation states of islet-infiltrating Tregs and the impact of CD137 deficiency.

ORGANISM(S): Mus musculus

PROVIDER: GSE269611 | GEO | 2025/01/03

REPOSITORIES: GEO