The role of Spp1 in pancreatic cancer

ABSTRACT: We performed RNA-seq analysis on Spp1 wild-type and CRISPR/Cas9-mediated Spp1 knock out pancreatic tumour organiod from Pdx1-Flp;KrasFSF-G12D;Trp53frt/frt; Vim-EGFP (KPFV) mice. We compared the transcriptome between these two groups of them with the aim to understand their molecular signatures and the relevance to human pancreatic ductal adenocarcinoma subtypes.

ORGANISM(S): Mus musculus

PROVIDER: GSE269971 | GEO | 2025/08/11

REPOSITORIES: GEO