Genomics

Dataset Information

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HSD17B14 induction in breast cancer cell lines


ABSTRACT: The 17beta-hydroxy steroid dehydrogenase family is involved in the fine tuning of conversion of different substances such as steroids, retenoids and fatty acids. The expression of HSD17B14 has been correlated to better prognosis in breast cancer. The function of HSD17B14 is still not known, but it may convert estradiol to estrone. We transfected breast cancer cell lines with a HSD17B14-containing plasmid and compared with mock-transfected samples. The influence on global gene expression was examined with microarrays.

ORGANISM(S): Homo sapiens

PROVIDER: GSE26998 | GEO | 2015/03/01

SECONDARY ACCESSION(S): PRJNA136939

REPOSITORIES: GEO

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