Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The drug-elicitable alternative splicing module for tunable vector expression in the heart

ABSTRACT: RNA Seq datasets from WT or AAV-injected mice treated with 10 mg/kg risdiplam or solvent. RNA Seq datasets from plasmid-transfection HEK293T cells treated with 1uM risdiplam or DMSO.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE270445 | GEO | 2025/04/13

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Effect of ∆Np63 deletion on epigenomic rewiring via differential H3K27ac and H3K27me3 enrichment

Project description:Basal cells were isolated from an influenza-infected non-tamoxifen treated Krt5CreERT2; RFP; ∆Np63flox/flox mouse and cultured, allowing for inducible ∆Np63 deletion in vitro. These basal cells were plated as monolayers and treated with 1uM 4OHT for +4OHT (∆Np63 KO) or equivalent volume DMSO for -4OHT (solvent only, ∆Np63 WT) for 48 hours. Technical triplicates of ∆Np63 WT and ∆Np63 KO treated in parallel were harvested for each IP for p63 and each histone modification for ChIP-seq.

2022-11-11 | GSE216159 | GEO

Effect of ∆Np63 deletion on plasticity of post-injury lung basal cells

Project description:Basal cells were isolated from an influenza-infected non-tamoxifen treated Krt5CreERT2; RFP; ∆Np63flox/flox mouse and cultured, allowing for inducible ∆Np63 deletion in vitro. These basal cells were plated as monolayers, airway organoids, and alveolar organoids and treated with 1uM 4OHT for +4OHT (∆Np63 KO) or equivalent volume DMSO for -4OHT (solvent only, ∆Np63 WT). Technical triplicates of ∆Np63 WT and ∆Np63 KO were harvested for each growth condition for RNA sequencing.

2022-11-11 | GSE216160 | GEO

Effect of CYP1B1 inhibition and estrogens on pulmonary vascular smooth muscle cells

Project description:PMVEC treated with scrambled siRNA, or siRNA to CYP1B1 are treated with vehicle, 1uM E2, or 1uM 16aOHE

2024-02-01 | GSE166006 | GEO

Investigation of the arsenic regulated proteome of PML bodies

Project description:A proteomic analysis of PML bodies purified from U2OS cells expressing YFP-PMLV either treated or not with 1uM arsenic for 2 hours, in comparison with parallel purifications from wt-U2OS cells treated identically.

2023-01-05 | PXD030330 | Pride

The drug-elicitable alternative splicing module for tunable vector expression in the heart

Project description:The drug-elicitable alternative splicing module for tunable vector expression in the heart

| PRJNA1126649 | ENA

Temporal Insights into Molecular and cellular responses during rAAV production in HEK293T cells

Project description:To understand the dynamic role of HEK293T cells at different cellular states post-transfection we have performed a comprehensive comparative proteome profiling of the host cell system post-transfection at 24, 48, and 72 hpt. For this study, we developed an in-house label-free HEK293T-AAV spectral library

2024-08-09 | PXD046574 | Pride

HIV Nef transfected HEK293T cell culture and HIV mock transfected HEK293T cell culture [miRNA]

Project description:Purpose: Comparison of RNA-sequencing datasets obtained from exosomes of Nef-transfected and Mock-transfected HEK293T cells Methods: Assessment of RNA content of exosomes produced by Nef-transfected HEK293T cells and and Mock-transfected HEK293T cells Results: Differences in a set of microRNAs Conclusions: Nef-transfection induces changes in the microRNA content of exosomes

2018-11-18 | GSE122656 | GEO

HIV Nef transfected HEK293T cell culture and HIV mock transfected HEK293T cell culture [mRNA]

Project description:Purpose: Comparison of RNA-sequencing datasets obtained from exosomes of Nef-transfected and Mock-transfected HEK293T cells. Methods: Assessment of RNA content of exosomes produced by Nef-transfected HEK293T cells and and Mock-transfected HEK293T cells. Results: Differences in a set of mRNAs. Conclusions: Nef-transfection might induces changes in the mRNA content of exosomes.

2018-11-18 | GSE122655 | GEO

RNA-seq of YB5 and MCF7 treated with different doses of decitabine

Project description:RNA-seq was performed after YB5 cells were treated with 1uM decitabine, and MCF7 cells were treated with 100nM decitabine

2017-01-31 | GSE74251 | GEO

Project description:RNA-Seq of GM03813 fibroblasts treated with DMSO, risdiplam, or branaplam

| PRJNA758038 | ENA