Polyploid cancer cells reveal signatures of chemotherapy relapse [scRNA-seq]

ABSTRACT: Treatment of PC3 and MDA-MB-231 cell lines with sublethal doses of docetaxel or cisplatin in vitro resulted in induction of polyploid cancer cells. Single cell copy RNA-sequencing was conducted to understand resistance of polyploid cancer cells to chemotherapy.

ORGANISM(S): Homo sapiens

PROVIDER: GSE270568 | GEO | 2024/09/13

REPOSITORIES: GEO