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A high-temporal-resolution single-cell transcriptomic atlas of pre- to post-implantation transition in mouse embryogenesis

ABSTRACT: Embryo implantation is a pivotal phase in early mammalian embryonic development. However, the mechanisms guiding the embryos from pre- to post-implantation remain largely elusive. Here, we present a comprehensive transcriptomics atlas of mouse embryo implantation, characterized with high temporal resolution. We collected mouse embryos at distinct stages— before, during, and after implantation— and performed single-cell RNA sequencing. Our analysis of 22,171 single-cell transcriptomes elucidates the developmental trajectories encompassing the entire implantation process.

ORGANISM(S): Mus musculus

PROVIDER: GSE270803 | GEO | 2025/07/30

REPOSITORIES: GEO

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