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Modulating immune cell fate and inflammation through CRISPR-mediated DNA methylation editing [RNA-seq, transdifferentiation]

ABSTRACT: We examine the differential transcriptional dynamics during the C/EBPa-driven transdifferentiation of B-cells into iMacs in cells with experimentally induced hypermethylation of the IL1RN gene promoter.

ORGANISM(S): Homo sapiens

PROVIDER: GSE270876 | GEO | 2025/06/02

REPOSITORIES: GEO

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