The comparison of gene expression profile in the amygdalae between the wild-type and neuropsin knock-out mice

ABSTRACT: Extracellular proteolysis contributes to fear-associated responses by facilitating neuronal plasticity at the neuron-matrix interface. A serine protease neuropsin is critical for stress-related plasticity in the amygdala by regulating the strength of EphB2/NMDA receptor interaction controlling the expression of fear-related genes and anxiety-like behavior. To look for downstream effects of neuropsin-mediated disassembly of the EphB2/NR1 complex we analyzed gene expression in the amygdalae of wild-type and neuropsin-/- mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE27088 | GEO | 2011/05/13

SECONDARY ACCESSION(S): PRJNA137469

REPOSITORIES: GEO