HDAC1 regulates effector CD8+ T cell differentiation during chronic viral infection

ABSTRACT: Hdac1 is a known epigenetic regulator of gene expression. The aim of this study is to investigate whether Hdac1 influences CD8+ T cell fate during chronic infection. We demonstrate that the genetic ablation of Hdac1 reduces the generation of Tex-Int cells

ORGANISM(S): Mus musculus

PROVIDER: GSE271531 | GEO | 2025/04/23

REPOSITORIES: GEO