Genomics

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MiRNA microarray expression from glioblastoma & astrocytes under 100V/m 48hr dcEF stimulation & sham


ABSTRACT: Direct current electric field mimicking a physiological electrical field from transepithelial potential difference can direct cell migration (electrotaxis)and cellular signaling. While the transcriptome in dcEF has been reported and more studied, the miRNA expression of cells under dcEF stimulation is less understood. We use a reversibly sealed dcEF stimulation bioreactor to apply uniform dcEF to glioblastoma cell lines and primary astrocytes and investigate if dcEF can induce differential expression of cellular miRNA and exosomal miRNA expression that can regulate the gene expression

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE271714 | GEO | 2025/07/11

REPOSITORIES: GEO

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