Transcriptomics

Dataset Information

22

Comparative gene expression profiles induced by PPARγ and PPARα/γ agonists in human hepatocytes


ABSTRACT: Transcriptomic profiling of primary human hepatocytes after treatment with 2 glitazones (TRO and ROSI) and 2 glitazars (MURA and TESA) Singe-Channel Samples: We have analysed changes in gene expression profiles in primary human hepatocytes after a 24 h treatment with various concentrations of glitazones and glitazars Dual-Channel Samples: We have analysed changes in gene expression profiles in primary human hepatocytes and differentiated human hepatoma HepaRG cells after a 24 h treatment with various concentrations of glitazones and glitazars Overall design: Singe-Channel Samples: 5 condition experiments, control, TRO (3 concentrations) , ROSI (3 concentrations) , MURA (3 concentrations) and TESA (1 concentration) , biological replicates:2 to 4 Dual-Channel Samples: 5 condition experiments, control, TRO (3 concentrations) , ROSI (4 concentrations) , MURA (4 concentrations) and TESA (1 concentration) , biological replicates: 3

INSTRUMENT(S): Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)

ORGANISM(S): Homo sapiens  

SUBMITTER: rogue alexandra  

PROVIDER: GSE27183 | GEO |

SECONDARY ACCESSION(S): PRJNA137361

REPOSITORIES: GEO

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