Spinal cord organoids derived from human amniotic fluid iPSC recapitulate the diversity of cell phenotypes during fetal neural tube morphogenesis

ABSTRACT: We developed spinal cord organoids (SCOs) as an in vitro modeling system to help understand the pathophysiology of the spinal cord in myelomeningocele (MMC). The cell types and development of these SCOs was examined with scRNA sequencing.

ORGANISM(S): Homo sapiens

PROVIDER: GSE271944 | GEO | 2025/07/10

REPOSITORIES: GEO